CUSTOM ANTIBODY SERVICES

Goat Antibody Service

Antibody production in goats is essential when larger quantities of antiserum are needed and/or when an alternative immunization host is a requirement for an investigator's particular application.

Yen-de-Zyn (antigen design service)
$195FREE
Synthesis of optimally designed peptide:
  • General grade peptide (usually at 50-60% purity or higher)
  • Mass spectrometry included
  • Up to 15 amino acids in length
  • Remaining amount sent to investigator
    • $200

    ($15 per amino acid over 15 residues)

    Carrier Protein Conjugations:
  • Peptide to KLH (Keyhole Limpet Hemocyanin) or THY (Thyroglobulin) for immunization purposes.
  • Peptide to BSA (Bovine Serum Albumin), when necessary, for ELISA purpose.
    • $295
    Goat Antibody Production (1 goat)::
  • One priming immuniation, 4 bi-weekly boosters, test bleed, 1 final booster and production bleed
  • ~5 ml pre-immune serum
  • ~5 ml test bleed serum
  • Pre-immune vs. test bleed ELISA
  • 200 to 250 ml final antiserum
    • $1,095
    TOTAL
    $1,590 $1,490

    Investigators are also welcome to provide their own ready-to-use immunogen for antibody production. For goat antibody production in 1 goat using an investigator provided ready-to-use immunogen we ask that we are provided with about 12 mg of ready-to-use immunogen at a concentraiton of no less than 0.5 mg/ml preferably in 1X PBS, though any buffer is acceptable provided it does not contain high concentrations of denaturing agents (e.g. >4M Urea). Please contact us if the quantity of your immunogen is limiting. Also, we strongly encourage investigators to contact us prior to submitting their immunogen to ensure antibody production in goats is suitable to raise a potentially useful antibody.

    The price for Goat Antibody Service using an investigator provided ready-to-use immunogen in 1 goat is $1,095 per project.

    Our animal facility is NIH/OLAW/PHS assured, USDA certified, and IACUC regulated.

    For projects that require animal work to be conducted at an AAALAC accredited animal facility, please contact us.

    Due to its synthetic nature, the chemically synthesized peptide, when used as an immunogen, may not necessarily achieve the same effect as that of the native protein. The elicited antibody may not necessarily perform up to the investigator’s expectations due to a variety of factors that may exist in the investigators assay system (e.g. unknown post-translational modifications, low endogenous protein levels, protein processing events, reagents used, etc.). YenZym ensures only the quality of the peptide synthesized (by mass spectrometry) and guarantees specificity of the antibody response to the immunizing peptide (by ELISA). However, YenZym will try its best to help remedy the situation should antibody difficulty be encountered.

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